Research and Innovation Projects

Research areas

Cognition - Behavior and Technology

Ageing and Neurodegeneration

Mental illness

Cognitive rehabilitation and Neuropsychological intervention

Brain structure -Function & Biological markers

Grants

Selected

Support (M) Monitoring (A) And (R) Reminder (T) Technology (4) for (M) Mild (D) Dementia (SMART4MD)-European Comission – Research and Innovation Framework Programme. Horizon 2020 (2014 -2019 –IP del Consorci Sanitari de Terrassa (CST) –la institución líder del proyecto és la Anglia Rusking University- UK)

INtelligent system to empower Functional Independence of people with mild cogNItive impairmenTs (19342). EIT Health (European Union) (2019-2020)

T’ACTIVA, Terrassa Activa i Saludable. Projecte d’especialització i competitivitat territorial (pect) po FEDER 2014-2020

Entrenamiento cognitivo basado en recuerdos digitales para el deterioro cognitivo leve (Re-memory). Fundació Marató TV3 1021/97 (2014 –2018).

Obesidad y funcionamiento cerebral: Inflamación y estrés. Ministerio de Economía y Competitividad (2017-actualidad). CST-UB (IP del CST)

Executive function training in childhood obesity: food choice, quality of life and brain connectivity (TOuCH)”. Funding Agency La Marató TV3 Duration 2017-2020

Obesity and overweight: Biomarkers and Neuropsychology”. Funding Agency Ministerio de Educación y Ciencia. Duration 2014-2017 Description neural correlates on life span. Brain networks characterization.

Effectiveness of memory training program in adult with Attention Deficit Disorder with Hyperactivity. Awardes the Joan Costa I Roma award for Research (2012)

Obesity: Cognition, Neuroimaging and Genetics: Ministerio de Educación y Ciencia. Universidad de Barcelona (UB) & CST-HT. PSI2008-05803-CO2-02 (2008-2011-extended until June 2012). Lead Researcher subproject: Obesity: Cognition and Genetics.

Prospective Study of the effects of complementary chemotherapy with 5-flurouracilo, epirubicine and cyclophosphamida (FEC) with and without paclitaxel in patients diagnosed of breast cancer. Awarded the Joan Costa I Roma award for Research (2010)

Compared efficacy of two cognitive rehabilitation strategies in the treatment of disabled population with mild cognitive impairment CST-HT & Universidad de Oviedo & Universidad de Granada. Instituto Carlos III for the evaluation research of health services and technologies. FIS Technological Grant, PI08/90753 (2008-2010).

Assessment of the neuropsychological deficits in patients with +HIV with different levels of immunity and their relation to the antiretroviral treatment. CST-HT & Fundació de Lluita contra la SIDA Hospital Universitario “Germans Trias i Pujol. Fundación para la Investigación y la Prevención del SIDA en España (FIPSE) Grant (2002-2003)

Establishing neuropsychological subtypes of the schizophrenia in relation to the syndromic heterogeneity of the disorder: For diagnostic use and treatment orientation CST-HT. Fundació Seny Grant, 10 E/99 (2000-2002).

Regional cerebral blood flow study (SPECT) during a Frontal Activation Task before and after treatment with Risperidona in schizophrenic patients not treated previously. CST-HT. FIS Grant, 99/1083 (1999-2001)

Subsidized Research Projects

Randomized controlled study to compare the efficacy and security of two different pharmacological strategies on neurocognitive impairment in the HIV infection. TRIANT Study. Independent research study of Ministry of Health of Spain: EC10-320. (2010-2012).

Development of a brief instrument to assess the neurocognitive and motor function in patients infected by HIV. Grant from: Fundación para la Investigación del SIDA en España (FIPSE) 24673/07. (2007-2009).

Effectiveness of a memory training program in children with Attention Deficit Disorder with Hyperactivity. Given the Ferran Salsas i Roig Award for research projects (2010-2011).

Active projects

SMART4MD

The SMART4MD project aims the development and validation of a mobile management application for people with cognitive impairment. This mobile application is creator with the participation of people with cognitive impairment, carers and healthcare professionals. It has been carried out a study of feasibility prior to the clinical trial where the application has been tested, as well as the different elements of the test.

The feasibility study gave satisfactory results that allow start the clinical trial. The participants for the clinical trial display are 1,200 days (people with cognitive impairment and the main caregiver) and 4 centers participate in three countries (Spain, Sweden and Belgium). It is a randomized and randomized controlled trial with two groups: intervention (SMART application) and control. We will follow-up of 18 months. The measure of principal result is the quality of life of the person with cognitive impairment.

INFINITY

INFINITy is a technological solution developed to maintain the functionality and autonomy of the elderly who suffer from mild cognitive impairment, thus improving the quality of life of the person and their informal caregiver. To maintain this autonomy and independence, the INFINITy application offers support in a series of activities that are carried out both inside and outside the home (smart cities).

This technological solution is made up of a mobile application, card or any other material support that works with Near Field Communication (NFC) technology and for beacons with bluetooth technology that are placed at strategic points in the city (points of interest). NFC cards make it easier for the person to perform an action with their mobile phone, such as sending a predetermined message to a relative without interacting with the device, simply by bringing it closer to the NFC card. And with reference to the beacons, they provide reminders or health advice when the person goes next to that location. These notifications are semantically related to the point of interest and aim to promote a healthy aging.

T'activa project

T’ACTIVA

T'ACTIVA is a project to encourage innovation around the development of a mobile application, through which citizens can access a platform that intends to connect to users and motivate them to improve the Your health and participate in making Terrassa a healthier city.

This project will invite you to propose ideas for the design of a digital platform based on two principles. The first is that it must include elements of reality (context) and, therefore, it is linked to a specific location that is its city. The second is that it should encourage participants to be linked to their context, increase their knowledge (learn) and participate to achieve the goals, which in this case are improving their health and that of the city.

The T'ACTIVA project focuses on the creative process that must necessarily imply the different municipal services, city agents (four-helix), which should help to define the problems and translate them into solutions in the field concrete (the city of Terrassa). This contextual meaning breaks down with global designs and is expected to make it easier for users to be involved in the construction of a more citizen citizen health promotion environment.

The involvement in the project of the different municipal services, of the citizens and of all the agents related to the development of talent, technology and innovative entrepreneurship interested in this field of opportunity is expected, with the intention of generating in Terrassa a pole of Attracting entrepreneurship, talent and investment linked to mobile solutions for healthy living in the city.

REMEMORY

Develop a Cognitive Training program (CT) for MCI based on life-logging captured by a Wearable Camera

The ReMemory Project has been one of the winners of the first edition of CRAASH Barcelona, ​​a 12-week program that helps European research teams launch their innovative devices to improve health and patient care. The teams move the search to the market guided by experts from CIMIT (Boston), the most experienced health accelerator in the world. CRAASH Barcelona is organized by Biocat in collaboration with CIMIT and EIT Health. This is one of the emblematic programs of Moebio, Biocat's initiative for acceleration and innovation.

The ReMemory Project benefits from the first agreement with CIMTI to promote innovation projects in the field of health. The Terrassa Health Consortium has had the opportunity to sign a pioneering agreement with the Center for the Integration of Medicine and Technologies (CIMTI). One of the projects of the Sanitary Consortium of Terrassa benefitted from this agreement is the ReMemory Project. The CIMTI will be in charge of supporting the work team of the ReMemory and facilitating the management to arrive at the market as soon as possible, since it could be a very important advance in the Catalan and global health system.

The CIMTI is a tool to promote projects based on innovative technologies applied to the health sector, promoted by the LEITAT Foundation and with an agreement with the Department of Health and the Catalan Quality and Assessment Agency (AQuAS), and a strategic alliance with the CIMIT of Boston

POBE3 project

POBE3

Childhood obesity is one of the most important health disorders of the XXI century, increasing the vulnerability to metabolic and cardiovascular diseases. Efforts for the prevention and/or treatment of obesity constitute, therefore, a worldwide priority. Previous studies have described changes in brain function associated with obesity. However, contradictory findings exist, suggesting the existence of intermediate factors that might explain the broad heterogeneity associated with obesity. The present project is aimed at determining the potential mediator role of inflammation and stress in the relationship between obesity and cognitive, neuroanatomical and functional brain changes.

Our working hypothesis is that inflammation and stress will potentially act as a mediator. To this aim, we will analyze data from 75 participants with obesity and 75 normal-weight participants (12-19 years old, 50% females, participants will be recruited as part of the coordinated project). We will perform multiple mediation analyses to test our hypothesis. Our results will shed light on what factors are associated with obesity and with the neurocognitive changes associated with obesity, and will open new therapeutic pathways for the prevention of childhood obesity

© 2019 Consorci Sanitari de Terrassa

Clinical Research Brain, Cognition and Behavior

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